In the Daily Maverick article of 23 November, ‘Fake news and Misinformation kill: How can you trust what you are told about Covid-19’, the ‘Scientists Collective’ (‘SC’) make the obvious point that, in the Internet age, there is a lot of misinformation about.

PANDA’s formation was premised on this very idea. Since March, we have been building a global multi-disciplinary team of doctors, geneticists, virologists, actuaries, economists, statisticians, lawyers and other professionals, guided by some of the finest scientists in the world from Oxford, Stanford and Harvard Universities.

This team’s purpose has been to consider all of the science and to separate the good science from the bad and promote the former. Whilst we have much in common with the SC, there is one important difference in our approach. PANDA believes that the purpose of science is to inform, not to prescribe. The article by the SC drips with condescension.

Whereas PANDA believes that the people of South Africa will do the right thing if they are empowered with accurate information, the SC sees them as lemmings who will march to their deaths if they are exposed to ‘dangerous information’.

The SC is composed of academics primarily from medical disciplines. Three of these academics were members of the now-disbanded Ministerial Advisory Committee (‘MAC’), which was responsible for government policy to date, including the devastating lockdowns. Most of the others are employed in state-funded universities. We had read their unceremonious ejection from the MAC as suggesting that they had tried to ‘speak truth to power’ (as they put it) to counter the profound irrationality of government policy, but their Daily Maverick article would suggest otherwise.

Poor quality of the data

The SC endorses certain sources of information. At the top of the list is the South African government’s website (despite the poor quality of the data the government is producing) and they hold up as impeccable sources of science the US Centers for Disease Control (‘CDC’) and the World Health Organisation (‘WHO’).

They say, for example, that South Africa should count on 390 000 Covid deaths, which number they arrive at by multiplying the South African population by an infection fatality rate published by the CDC. The CDC – whose July 0.65% infection fatality rate they reference – in September updated its analysis to prove precisely the point these scientists are denying – that, for the majority of the population, Covid infection presents less risk than the flu (which has an IFR of between 0.1% and 0.2%).

Here is the updated CDC data:

AgeCDC IFR
0-19 years0.003%
20-49 years0.020%
50-69 years0.500%
70+ years5.400%

Unlike Covid-19, flu is just as dangerous for children as it is for adults. According to the CDC, therefore, flu is in fact more than 30 times more dangerous for a child than Covid-19 and 5 times more dangerous than Covid-19 for people under 49. This is one of the reasons why PANDA supports focused protection.

The other source the SC suggests you trust, the WHO, on 14 October published a paper co-authored by famous epidemiologist John loannidis, which estimated that the IFR of the virus is ‘less than 0.2%’.

WHO

On 5 October, the WHO made a statement in which it advised that 10% of the world’s population is estimated to have been infected with Covid-19 (7.8 billion people). At the time of that statement, around 1 200 000 people had ostensibly died of Covid-19, meaning that the WHO was working with an estimate of the IFR of 0.14%.

The SC makes many errors in arriving at their 390 000 number – they used an outdated IFR, from a country that has little in common with South Africa and they entirely neglected the profound age-based fatality rates of Covid-19.

But the most egregious error in their calculation is that they apply their mangled fatality rate to the entire population of South Africa, thus perpetuating the myth of universal susceptibility.

It has been manifestly clear since the Diamond Princess papers in March and the Swedish serology studies in May that universal susceptibility is not a thing. Decades of viral immunology taught us never to expect such a thing and dozens of scientific papers now delineate the precise mechanisms of widespread pre-existing immunity against Covid-19.

Perpetuates the myth

The SC also irresponsibly perpetuates the myth that excess deaths in South Africa are caused by Covid-19. There is no science proving this and the South African Medical Research Council does not claim the deaths as Covid deaths.

PANDA has produced a paper examining the oddities in the excess death reporting and examining that reporting in detail. These reports show that the excess deaths over and above official Covid deaths are more likely deaths caused by lockdown.

In the United States, where better-quality data is generated and the citizenry better protected against the effects of lockdown, research has shown ‘no evidence that COVID-19 created any excess deaths. Total death numbers are not above normal death numbers.’

If Covid-19 hasn’t caused any excess death in countries that have measured its impact, something else has likely caused the excess death in South Africa.

The SC also says that although they initially recommended against masks, they now do recommend them and, although they ‘welcome debate’, masks are now ‘not up for debate.’ Confused? This in the same week that the only randomized control trial ever done on masks and Covid-19, which found no significant effect from masking, has been hotly debated around the world. One would think that if the science was so universally settled, it would be a cake walk to present really compelling evidence on masks. Support for mask-wearing does not exist in any of the randomized control trials that have been conducted, nor do mask mandates demonstrate any benefit in the epidemic curves of any of the countries or regions that have adopted them.

Derisory

This source lists the top-10 mask-wearing countries on the planet, with Brazil, third best, and Sweden, third worst. If you look at these countries’ deaths per million, you will see no correlation. To contend that cloth mask-wearing is not a controversial practice and that this is beyond debate by reputable people is derisory, especially when such contention follows the point that debate ‘is not suppressed’.

Providing almost comical evidence for their contention, the authors link to three advisories, none of which actually reference any specific and robust research. One even references an anecdote involving a sample size of two — yes, two — hairdressers.

The WHO, whom SC recommends you trust, in their latest advice on the use of masks states that ‘(at) present, there is no direct evidence (from studies on COVID-19 and in healthy people in the community) on the effectiveness of universal masking of healthy people in the community to prevent infection with respiratory viruses, including COVID-19,’ and ‘(at) the present time, the widespread use of masks by healthy people in the community setting is not yet supported by high quality or direct scientific evidence and there are potential benefits and harms to consider.’

As a result, the WHO only recommends the wearing of masks by the public in limited scenarios – notably by people who are symptomatic (i.e. obviously sick).

There are too many other factual errors in the SC article to cover here.

In the grip of irrationality

Much is made of the reliability of the WHO’s efforts. By way of illustration of how deeply in the grip of irrationality the WHO is, we recount the sorry story of its position on asymptomatic transmission, on which issue it performed a spectacular 180 degree pivot on 8 June.

In farcical fashion, this was unaccompanied by any evidence and occurred on the same day that its lead scientist, Maria van Kerkhove, confessed to what science has proved over and over again – that asymptomatic transmission was very rare. The WHO went short science & long politics, forcing poor Maria to say that asymptomatic transmission was common – in models, of course, because she had been entirely correct in saying that it was rare in the real world!

These are the antics of an organisation irretrievably captured by politics and therefore no longer in the business of public health.

The SC authors are mealy-mouthed about lockdowns. We will not be. All credible research demonstrates lockdowns to be singularly ineffective. Here is the NICD view on lockdowns, the view of Alex Lemond of the University of Pretoria and Professor Andrew Boulle of UCT.

It is not that we shouldn’t be worried about the disease. We are not ‘Covid-deniers’. It is simply that we shouldn’t be launching into panicky and destructive policies that contradict all pre-Covid science. SC members, when they were part of MAC, caused immense harm by encouraging government to implement lockdowns.

The virus is not particularly ‘deadly’. It is not really new, explaining why we are definitely not all susceptible to its disease. In the face of these facts, population-wide coercive practices are expected to lead to increased Covid mortality, which is exactly what the astronomic South African age-based mortality tells us they have done.

Should have had fewer deaths

Make no mistake, South Africa has not fared well. Given the age of our population, we should have had fewer deaths than we have had. The evidence suggests this poor performance is not the result of not doing enough lockdown, but doing too much. The policies that led to this disastrous state of affairs were motivated by science that members of the SC produced. This perhaps explains their condescending tone and their confusion as to whether they are tolerant of debate and whose contentions they are prepared to admit to it.

‘Scientists who collude with governments to legitimise unscientific approaches have been a feature of many country responses across the globe and need to be challenged,’ the SC says.

Quite right, but it is more than apparent that the process of such challenging needs to start with introspection on the part of these scientists.

As far as we can see, they are net contributors to the hysteria and pseudoscience that has driven such responses. They need to listen to the words of this scientist, show some humility in the face of their past panic, and help to restore life in South Africa to normal as quickly as possible.

To do otherwise will leave them judged by history in a most unfortunate light.

*The Daily Maverick declined to publish this article.

[Picture: Tumisu from Pixabay]

The views of the writers are not necessarily the views of the Daily Friend or the IRR

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Nick Hudson is co-ordinator of PANDA (Pandemics Data and Analytics), a multidisciplinary group seeking to inform Covid policy, and a founding partner of private equity firm, SANA Partners. Hudson has extensive experience in the financial sector and is a Fellow of the Institute and Faculty of Actuaries. He spent a decade at RMB Ventures, four years at Stern Stewart & Co. in New York City, and six with the Swiss Re Group. Shayne Krige has over a decade of experience as a corporate lawyer in Europe and has spent the past nine years practising in South Africa. He is currently a director in the corporate law department of a top-tier law firm, and has worked on a diverse range of cases, including major corporate restructurings, saving butterflies from extinction, assisting victims of police torture and setting up a well-known online start-up. PANDA considers explanations that allow us to count the human costs of COVID-19 responses globally. PANDA is a collective of leading scientists, actuaries, economists, data scientists, statisticians, medical professionals, lawyers, engineers and businesspeople working as a collective to replace bad science with good science. PANDA members work voluntarily, offering their skillset to contribute to informed policy- and decision-making. PANDA is not aligned with any political entity and is funded by its members, income from speaking engagements, and the public.